|
KMID : 0895420010110030198
|
|
Journal of Korean Society of Occupational and Enviromental Hygiene
2001 Volume.11 No. 3 p.198 ~ p.205
|
|
|
Inhalation toxicity assesment of C.I.No. Reactive Red 195 in Rats
|
|
정용현/Chung, Yong Hyun
한정희/송경석/김현영/이성배/유일재/Han, Jeong Hee/Song, Kyung Seuk/Kim, Hyeon Yeong/Lee, Sung Bae/Yu, Il Je
|
|
|
Abstract
|
|
|
Many Reactive dyes have been used in occupational settings without knowing their toxicity and health hazard information. To investigate the toxicity of reactive dye, C.I.No. reactive Red 195 was exposed to male and fem Sprague Dawley rats by inhalation for 28 days. The rats were exposed C.I.No. Reactive Red 195 for 6hrs per day and 5day per week. The concentrations for the inhalation exposure were 0, 10, 40 and 160 ㎎/㎥, After 4 weeks of exposure, ra were examined for exposure related changes throug? pathology, blood biochemistry and hematology.
There were no does related changes including clinical signs, body weight and relative organ weight changes, hematological and biochemical and histopathological findings.
The results indicate that no observed adverse effect level(NOAEL) of 28 days inhalatrion toxicity test for C.I.No. Reactive Red 195 was 160 ㎎/㎥.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|